Robert V O'Toole Selected Research

Surgical Wound Infection

7/2022	The Application of Bayesian Methods to Help Interpret the VANCO Trial Results.
4/2022	Does cumulative topical antibiotic powder use increase the risk of drug induced acute kidney injury in fracture patients?
12/2021	Admission Hyperglycemia Is a Risk Factor for Deep Surgical-Site Infection in Orthopaedic Trauma Patients.
6/2021	Risk factors for treatment failure of fracture-related infections.
1/2021	Intraoperative Tobramycin Powder Prevents Enterobacter cloacae Surgical Site Infections in a Rabbit Model of Internal Fixation.
1/2021	Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial.
1/2021	Vancomycin Powder Use in Fractures at High Risk of Surgical Site Infection.
1/2021	Topical Vancomycin Powder Decreases the Proportion of Staphylococcus aureus Found in Culture of Surgical Site Infections in Operatively Treated Fractures.
3/2020	Effect of Extended Prophylactic Antibiotic Duration in the Treatment of Open Fracture Wounds Differs by Level of Contamination.
1/2020	Effectiveness of Iodophor vs Chlorhexidine Solutions for Surgical Site Infections and Unplanned Reoperations for Patients Who Underwent Fracture Repair: The PREP-IT Master Protocol.

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Robert V O'Toole Research Topics

Disease

35	Wounds and Injuries (Trauma) 04/2022 - 11/2009
21	Infections 07/2022 - 11/2010
16	Surgical Wound Infection 07/2022 - 10/2013
7	Compartment Syndromes 01/2022 - 10/2009
7	Open Fractures (Compound Fracture) 12/2021 - 11/2010
6	Pain (Aches) 10/2020 - 02/2012
5	Tibial Fractures (Fracture, Tibial) 01/2022 - 12/2016
3	Pulmonary Embolism 03/2022 - 11/2017
3	Venous Thromboembolism 12/2021 - 01/2018
3	Hip Fractures (Intertrochanteric Fractures) 10/2021 - 06/2020
3	Femoral Neck Fractures 12/2020 - 06/2020
3	Femoral Fractures (Femoral Fracture) 02/2020 - 11/2009
3	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 02/2020 - 11/2009
2	Coinfection 01/2022 - 06/2021
2	Shock 12/2020 - 11/2009
2	Hemorrhage 01/2020 - 11/2017
2	Tibial Plateau Fractures 02/2017 - 12/2016
2	Arthritis (Polyarthritis) 11/2016 - 03/2014
1	Acute Kidney Injury (Acute Renal Failure) 04/2022
1	End Stage Liver Disease 03/2022
1	Fibrosis (Cirrhosis) 03/2022
1	Venous Thrombosis (Deep-Vein Thrombosis) 03/2022
1	Hemorrhagic Shock 02/2022
1	Osteonecrosis (Kienbock's Disease) 02/2022
1	Ankle Fractures 01/2022
1	Alcoholism (Alcohol Abuse) 12/2021
1	Soft Tissue Injuries (Soft Tissue Injury) 12/2021
1	Thrombosis (Thrombus) 01/2021
1	Vascular System Injuries 01/2021
1	Staphylococcal Infections 01/2021
1	Multiple Organ Failure (MODS) 12/2020
1	Periprosthetic Fractures 08/2020
1	Chronic Pain 03/2020
1	Leg Injuries (Leg Injury) 10/2018
1	Atherosclerosis 01/2018
1	Hematoma 01/2018
1	Persistent Infection 12/2016

Drug/Important Bio-Agent (IBA)

11	Anti-Bacterial Agents (Antibiotics)IBA 04/2022 - 11/2010
7	Vancomycin FDA LinkGeneric 07/2022 - 01/2021
7	PowdersIBA 07/2022 - 01/2021
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2021 - 01/2018
4	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2021 - 01/2018
3	Local Anti-Infective Agents (Antiseptics)IBA 04/2022 - 01/2020
3	Vitamin D FDA LinkGeneric 10/2021 - 06/2020
3	Oxygen (Dioxygen)IBA 05/2014 - 10/2013
2	Tobramycin (Nebcin)FDA LinkGeneric 04/2022 - 01/2021
2	Pharmaceutical PreparationsIBA 04/2022 - 12/2021
2	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 02/2014
2	SolutionsIBA 03/2021 - 01/2020
2	Povidone-Iodine (Betadine)FDA LinkGeneric 03/2021 - 12/2016
2	Lactic Acid (Lactate)FDA LinkGeneric 12/2020 - 11/2009
2	Morphine (MS Contin)FDA LinkGeneric 01/2019 - 06/2016
1	SodiumIBA 03/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	Blood Glucose (Blood Sugar)IBA 12/2021
1	chlorhexidine gluconate (Dyna-Hex)FDA LinkGeneric 03/2021
1	antineoplaston A10 (A 10)IBA 03/2021
1	First Generation CephalosporinsIBA 01/2021
1	MetalsIBA 01/2021
1	Penicillins (Penicillin)FDA Link 01/2021
1	AgarIBA 01/2021
1	AminoglycosidesIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 03/2020
1	ChlorhexidineIBA 01/2020
1	Hydromorphone (Dilaudid)FDA LinkGeneric 01/2019
1	Analgesics (Analgesic Drugs)IBA 01/2019
1	Inosine Monophosphate (IMP)IBA 10/2018
1	Contrast MediaIBA 01/2018
1	A 7 (A-7)IBA 02/2017
1	SmokeIBA 06/2016
1	Narcotics (Narcotic Analgesics)IBA 06/2016

Therapy/Procedure

8	Surgical Amputation (Amputations) 02/2022 - 08/2011
6	Fracture Fixation 03/2022 - 12/2020
6	Fasciotomy 02/2022 - 10/2009
4	Length of Stay 03/2022 - 02/2012
3	Resuscitation 02/2022 - 11/2009
3	External Fixators 12/2021 - 07/2014
3	Aftercare (After-Treatment) 03/2020 - 12/2016
2	Intramedullary Fracture Fixation 12/2021 - 11/2010
2	Traction 11/2021 - 11/2012
2	Physical Therapy Modalities (Physical Therapy Technique) 06/2021 - 02/2012
2	Antibiotic Prophylaxis 01/2021 - 03/2020
2	Arthroplasty 12/2020 - 03/2014
2	Mechanical Ventilators (Ventilator) 11/2020 - 02/2020
2	Therapeutics 10/2020 - 03/2020
2	Hip Replacement Arthroplasty (Total Hip Replacement) 08/2020 - 11/2016
2	Orthopedic Procedures 01/2020 - 10/2013
1	Osteotomy 02/2022
1	Operative Surgical Procedures 03/2021
1	Reoperation 01/2021
1	Debridement 01/2021
1	Tourniquets 11/2020
1	Duration of Therapy 10/2020
1	Tracheostomy 02/2020
1	Decompression 07/2019
1	Chemoprevention 01/2018
1	Subcutaneous Injections 11/2017
1	Bone Transplantation (Bone Grafting) 10/2017
1	Open Fracture Reduction 12/2015